kompositioner, vilka anvaends vid framstaellning av mikropartiklar som skall extruderas och vilka aostadkommer that foerlaengt frigivande av that biologiskt aktivt medel, och de saolunda erhaollna mikropartiklarna.

摘要

1. A composition for the preparation by extrusion of microparticles permitting a prolonged release of a biologically active substance, which composition consists of a biologically active substance, one or more non-hydrophilic polymers and from 10 to 40% by weight either of a mixture of at least two lipid excipients one of which has the property of dissolving or gelling the polymer or polymers and the other has lubricating properties or of a lipid excipient having both the property of dissolving or gelling the polymer or polymers and lubricating properties, and, if appropriate, one or more additives chosen from diluents and antistatic agents.