Purified lymphadenopathy and acquired immune deficiency syndrome virus and envelope antigens of this virus, method for obtaining this virus and these envelope antigens of this virus, uses of this virus or of these antigens in the preparation of immunogenic compositions or for the diagnosis of the abovementioned pathologies

摘要

Purified material (I) contg. the polypeptide back bone of a glycoprotein of molecular wt. about 110,000, or antigen of lower molecular wt. derived from it, is new. (I) is recognised by sera of human origin and contg. antibodies against the virus of lymphadenopathies (LAV) or acquired immune deficiency syndrome (AIDS). Peptides corresp. to the aminoacid sequences deducible from proteins encoded by LAV DNA are new, when defined by specific residues, e.g. 12-32, 37-46, 49-79, 88-153 etc.