PROCESS FOR THE PRODUCTION OF /+/ AND /-/-2-/M-CHLORINE-PHENYL/-5,6-TRIMETHYLENE-5,6-DIHYDRO-PYRIMIDIN-4/3H/-ON

摘要

(+) and (-) -2-(m-chlorophenyl)-5,6-trimethylene -5,6-dihydro-pyrimidin- 4 3H -one are prepd. from the racemic cpd. by salt formation with dibenzoyl d-tartaric-acid. The salt of the (+) enantiomer crystallises, is filtered and the (+) enantiomer is liberated from the crystalline salt wa base. - The (-) enantiomer remaining in the mother liquor is liberated with a base and sepd. The resulting pure (+) and (-) enantiomers are opt. further purified by crystallisation.