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COMPOSITION COMPRISING BOVINE GROWTH HORMONE CONTAINING A¹VALINE NEAR POSITION 126
COMPOSITION COMPRISING BOVINE GROWTH HORMONE CONTAINING A¹VALINE NEAR POSITION 126
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机译:126位元左右包含牛生长激素的牛生长激素的成分
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摘要
A method for preparing polypeptides in bacteria with an alanine rather than a methionine at the N-terminus. The DNA sequence expressed has an alanine codon immediately following from at least one methionine codon, and allows for the expression of polypeptides having the amino acid sequence essentially the same as such naturally occurring eucaryotic protein as various bovine and porcine somatotropin species. In another important embodiment, the invention provides a class of compositions comprising certain valine-containing somatropin species which increase milk production in lactating mammals to a significantly greater extent than otherwise-identical leucine somatotropin species.
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