VACCINE FOR TREATMENT OF TRICHOPHYTOSIS CAUSED BY TRICHOPHYTON MENTAGROPHYTES

摘要

The vaccine for prophylaxis and treatment of trichopytosis caused by Trichophyton mentagrophytes comprises a suspension of microconidia of the immunogenic Trichophyton mentagrophytes strain No. 135/1963 in a physiological solution with a pH of 6.2-7.0 in an amount of 15-25 min microconidia per 1 ml of the physiological solution having 8-25 mln of viable microconidia. A method for preparing the vaccine comprises growing the fungus culture Trichophyton mentagrophytes on a nutrient medium containing sources of carbon, nitrogen, biologically active compounds till an optimal accumulation of microconidia, separation of the resulting biomass, homogenization thereof to give a suspension of individual cells of the microorganism and drying of the resulting suspension. A method for prophylaxis and treatment of trichophytosis caused by the pathologenic microorganism Trichophyton mentagrophytes comprising intramuscular injection of the vaccine to animals at the inner side of the thigh thereof in a dose of 1 to 4 ml twice at an interval of from 7 to 10 days.