new derivatives of 6 - methoxy - 2 - acetylnaftalenoxim derivatives, which have analgesic, antipyretic and anti - inflammatory properties

摘要

The invention concerns 6-methoxy-2-acetylnaphthalene oxime derivatives of the general formula IMAGE in which R1 and R2 each represent a lower alkyl radical, or form, in association with the nitrogen atom to which they are linked, a saturated heterocyclic group, and the acid addition salts thereof with physiologically acceptable acids. These derivatives have analgesic, antipyretic and anti-inflammatory activity and can be made up into pharmaceutical compositions in tablet, capsule, suppository and the like forms. The derivatives of the invention may be prepared by reacting the corresponding 2-acetyl-6-methoxynaphthalene oximes with an appropriate substituted halogeno-ethylamine.