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pharmaceutical composition containing specific therapeutic properties against the acute pulmonary oedema, some states of shock and the iperfibrinolisi

机译:药物组合物,其具有针对急性肺水肿,某些休克状态和纤维蛋白原的特定治疗特性

摘要

Pharmaceutical compositions for use in the relief of acute pulmonary edema, different types of shock including anaphylactic shock, shock induced by bacterial endotoxins, and hyperfibrinolysis induced by substances which activate plasminogen, consist of solutions of an ester of L-arginine with an aliphatic alcohol in water at a pH between 5.5 and 8.5. The compositions may be provided in unit dosage form containing 0.25-100 mg of active substance and are administered through the parenteral route. The esters may be provided in the form of a salt with a pharmaceutically acceptable organic or inorganic acid. The esters may be with methyl or ethyl alcohol. The compositions are more effective than aspirin and aprotinin.
机译:用于缓解急性肺水肿,包括过敏性休克在内的不同类型的休克,细菌内毒素引起的休克以及激活纤溶酶原的物质引起的超纤维蛋白溶解的药物组合物,由L-精氨酸的酯与脂肪醇组成。 pH在5.5到8.5之间的水。该组合物可以以含有0.25-100mg活性物质的单位剂型提供,并通过肠胃外途径给药。所述酯可以与药学上可接受的有机或无机酸成盐的形式提供。该酯可以与甲醇或乙醇。该组合物比阿司匹林和抑酶肽更有效。

著录项

  • 公开/公告号IT1127321B

    专利类型

  • 公开/公告日1986-05-21

    原文格式PDF

  • 申请/专利权人 ITALFARMACO SPA;

    申请/专利号IT19790028416

  • 发明设计人 SPORTOLETTI GIANCARLO;BAGLIONI ALESSANDRO;

    申请日1979-12-28

  • 分类号A61K;

  • 国家 IT

  • 入库时间 2022-08-22 07:39:09

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