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mixed salts of amino acids essential or semi essential and their like nitrogen, and their use in the treatment of renal and hepatic impairment
mixed salts of amino acids essential or semi essential and their like nitrogen, and their use in the treatment of renal and hepatic impairment
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机译:必需或半必需氨基酸及其类似氮的混合盐,及其在肾脏和肝功能不全的治疗中的用途
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摘要
Novel compounds are prepared by reacting essential or semi-essential amino acids with nitrogen-free analogues thereof, particularly alpha-keto and/or alpha-hydroxy analogues. The mixed salt reaction products are precursors of essential and semi-essential amino acids in the body, and mixtures of the salts are useful in the treatment of renal and hepatic disorders characterized by protein intolerance leading to deficiencies of various essential and semi-essential amino acids in the body. They may also be useful in the treatment of nitrogen wasting disorders and protein malnutrition. The novel compounds are generally far more palatable and soluble in aqueous solutions than the individual essential or semi-essential amino acids, nitrogen-free analogues thereof, or simple mixtures of these.
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