This invention relates to a compound in substantially pure form, selected from: (a) alcohols having the following structural formulae 1a, 1b and 1c: CHEM where for 1a, R1 = H, and R2 = OH, for 1b, R1 = R2 = H, and for 1c, R1 = R2 = OH; (b) phosphates having the following structural formulae 2a, 2b, and 2c: CHEM where for 2a, R1 = H, and R2 = OH, for 2b, R1 = R2 = H, and for 2c, R1 = R2 =OH; (c) esters of the phosphate function of the phosphates of (b) and further pyranone phosphates designated CL 1565-A, CL 1565-B, and CL 1565-T having the following structural formulae 3a, 3b, and 3c, respectively: CHEM where for 3a, R1 = H, and R2 = OH, for 3b, R1 = R2 = H, and for 3c, R1 = R2 = OH; (d) acyl esters of the alcohols of (a) and of the pyranone phosphates of (c); (e) the compound designated CL 1565-PT-3; and (f) the pharmaceutically acceptable salts of the phosphates of (b), the pyranone phosphate esters of (c), the pyranone acyl esters of (d), and CL 1565-PT-3. The invention also provides for the production of such compounds. The compounds possess anti-tumor activity.
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