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A procedure to produce phosphate diesters and triesteres acid derivatives and octadecapentanoico FOSFA - piranona Cough

机译:一种生产磷酸二酯和三酯酸衍生物和十八碳二烯酸FOSFA的方法-吡罗那纳咳嗽

摘要

Process for producing phosphate diesters and triesteres octadecapentanoico acid derivatives and phosphate piranona.The Function consists of sterified phosphate Phosphates of formula (i) forms (I1, I2 and I3) and phosphate piranona of formula (ii) Sense (II1, II2, II3, with diazomethane in cold and a Solvent such as Methanol to obtain the triesteres acid diesters and octadecapentanoico and fosf Piranona Atos.Being R1 H in (I1, I2, II1 and II2 and Oh (I3); and II) R2, oh (I1, i3, III and II) and H (II1 and II2) CL 1565 - 1365 - B (ii-2); and (ii) CL 1565 - T. Used as antitumor, cytotoxic or antileucemicos.
机译:制备磷酸二酯和三酯十八碳烷酸衍生物和磷酸吡喃酮的方法。该功能由式(i)形式(I1,I2和I3)的磷酸酯化磷酸盐和式(ii)式(ii)Sense(II1,II2,II3,在冷条件下用重氮甲烷和甲醇等溶剂制得三酯酸二酯,十八碳二烯酸和fosf Piranona Atos.R1 H在(I1,I2,II1和II2和Oh(I3);以及II)R2,哦(I1, i3,III和II)和H(II1和II2)CL 1565-1365-B(ii-2);和(ii)CL 1565-T.用作抗肿瘤药,细胞毒性药或抗白血病药。

著录项

  • 公开/公告号ES8602738A1

    专利类型

  • 公开/公告日1986-03-16

    原文格式PDF

  • 申请/专利权人 WARNER-LAMBERT COMPANY;

    申请/专利号ES19850540090

  • 发明设计人

    申请日1985-02-01

  • 分类号C07D309/32;A61K31/365;A61K31/665;C07F9/09;

  • 国家 ES

  • 入库时间 2022-08-22 07:37:41

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