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A process for the preparation of stable conjugates and covalently coupled polysaccharide-protein.
A process for the preparation of stable conjugates and covalently coupled polysaccharide-protein.
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机译:一种制备稳定的结合物和共价偶联的多糖-蛋白质的方法。
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摘要
Covalently modified bacterial polysaccharides and proteins; covalent conjugates of such polysaccharides linked by a bigeneric spacer, which permits proof of covalency and facilitates purification of conjugated materials, with immunogenic bacterial membrane or other proteins, which conjugates are useful components of bacterial vaccines; and methods of preparing such polysaccharides, proteins and conjugates and of confirming the covalency of the linkage between polysaccharides and proteins.
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