Procedure for the synthesis of 1 - (2,3 Dihydro 1,4 - benzodioxin - 2S - il) - 5 - (2,3 Dihydro 1,4 - benzodioxin) - il - 2R) - 3 - azapentan - 1R - 5S diol

摘要

Procedure for the synthesis of 1 - (2,3 Dihydro 1,4 - benzodioxin - 2S - il) - 5 - (2,3 Dihydro 1,4 - benzodioxin - il - 2R) - 3 - azapentan - 1R - 5S diol.Is to Hydrolyze a compound of formula (ii) or a mixture of isomers, containing a compound of formula (iii) which means rest and Bab aralifatico acyl or Rest, to get the 1 - (2,3 Dihydro 1,4 - benzodioxin - 2S - il) - 5 - (2,3 dihydro - 1.4 - benzodioxin - il - 2R) - 3 - azapetan - 1R - diol of 5s Formula (i) and their acid Addition Salts.The reaction is carried out in the presence of a Solvent such as a Lower alcohol such as Methanol, ethanol, propanol and isopropanol and at an elevated temperature, Low Boiling Point of the Solvent empleado.se pharmaceutically used for its antihypertensive effect and moderately bradicardico.