METHOD AND APPARATUS FOR MOBILE PHASE ION CHROMATOGRAPHY AND MEMBRANE SUPPRESSION

摘要

Abstract of the DisclosureA mobile liquid phase including an ion exchange site-forming compound isdirected through a porous hydrophobic chromatographic separation mediumwithout permanently attached ion exchange sites. Such compounds include ahydrophobic counter-ion opposite in charge to the ionic species to be separated,which form reversible adsorptive bonds with the chromatographic medium. Theeffluent from the chromatographic medium is contacted with a membraneseparating a compartment for the effluent and one for a regenerant. Themembrane includes exchangeable ions capable of converting the co-ions of theion exchange site forming compoùnd to weakly ionized form. The ionic speciesare detected, suitably by a conductivity detector.