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Pyrrolo(2,3-d)carbazole derivatives, preparation thereof and their therapeutical use
Pyrrolo(2,3-d)carbazole derivatives, preparation thereof and their therapeutical use
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机译:吡咯并(2,3-d)咔唑衍生物,其制备及其治疗用途
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摘要
This invention relates to alkyl pyrrolo(2,3-d) carbazole-6-carboxylates having antianoxic, psychotropic and hemodynamic properties and to addition salts thereof; and to preparation of the same by a synthesis sequence starting from a tryptamine and a 3-halopyruvate and involving a rearrangement of an addition compound with an aldehyde, said rearrangement being effected by Nb-alkylation of the aforementioned addition compound; and to pharmaceutical compositions containing the same; and to tetrahydroazepinoindoles used in the preparation of the same.
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