Stabilization of tetrahydrofolic acid and serine hydroxymethyltransferase in reaction mixtures for the enzymatic cynthesis of L-serine

摘要

A method of stabilizing tetrahydrofolic acid and serine hydroxymethyltransferase in reaction mixtures for the enzymatic synthesis of L-serine by addition to the reaction mixture of a reducing agent or a mixture of reducing agents and by the addition of a high concentration of THF relative to a catalytic amount is disclosed.