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Derivatives of cephalosporins, their process of separation and antibiotic drugs containing the said derivatives

机译:头孢菌素的衍生物,其分离过程以及含有所述衍生物的抗生素药物

摘要

The present invention relates to cephalosporins having the formula: ##STR1## in which COOA is an acidic radical, salt or ester, and R.sub.1 represents a group: ##STR2## in which R.sub.A and R.sub.B are H or alkyl or together form a cycloalkyl with the carbon to which they are bonded, R. sub.2 and R.sub.3 are H, alkyl or alkenyl, R.sub.4 and R.sub.5 are H, alkyl or alkenyl or together form a ring to the nitrogen atom with which they are bonded. This invention also relates to a process for the preparation of these compounds and to drugs containing them.
机译:本发明涉及具有下式的头孢菌素:其中COA是酸性基团,盐或酯,并且R.sub.1表示基团:## STR2 ##,其中,R和R B是H或烷基或与它们所键合的碳一起形成环烷基,R 2和R 3是H,烷基或烯基,R 4和R 5 .5是氢,烷基或烯基,或一起与它们所键合的氮原子形成环。本发明还涉及这些化合物的制备方法和含有它们的药物。

著录项

  • 公开/公告号US4578377A

    专利类型

  • 公开/公告日1986-03-25

    原文格式PDF

  • 申请/专利权人 SANOFI;

    申请/专利号US19850723709

  • 发明设计人 BERNARD LABEEUW;ALI SALHI;

    申请日1985-04-16

  • 分类号A61K31/545;C07D501/34;

  • 国家 US

  • 入库时间 2022-08-22 07:29:22

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