Preparationof 1,4-lactones of 3,6-anhydrohexanoic acids

摘要

The invention is a process for the preparation of a 1,4- lactone of 3,6- anhydrohexanoic acid which comprises refluxing a 1,4- or 1,5-lactone of pentahydroxyhexanoic acid, or an aqueous solution of pentahydroxyhexanoic acid in an organic reaction media which azeotropes with water in the presence of an inorganic acid, under conditions such that a 1,4-lactone of 3,6-anhydrohexanoic acid is formed.