IONTOPHORESIS INTERMEDIARY MATERIAL AND CONTACT SOLUTION FOR THE TREATMENT OF CHRONIC PAIN SYNDROMES

摘要

A method of treating chronic pain is disclosed which comprises the step of topically administering to the skin of a human patient, 1 to 100 . mu.g/cm.sup.2 of body surface of a compound of the Formula (I) ##STR1## in which R is --CH.sub.3 or --CHOPPR.sup.1 is methoxy or amino;PPR.sup.2 is hydrogen, hydroxyl or acetoxy;P PR.sup.3 is hydrogen or ethyl;PP R.sup.4 and R.sup. 5 together form a valency bond or an epoxy bridge, or R.sup.4 is hydroxy or ethyl; andPPR.sup.5 is hydrogen; or a pharmaceutically acceptable acid addition salt thereof, by iontophoresis.