首页> 外国专利> METHOD OF INCREASING REPRODUCTIVE FUNCTION FOR BIRDS AND LIVESTOCKS AND OF FORMING SPERMA FOR THEIR REPRODUCTION

METHOD OF INCREASING REPRODUCTIVE FUNCTION FOR BIRDS AND LIVESTOCKS AND OF FORMING SPERMA FOR THEIR REPRODUCTION

机译:增加鸟类和牲畜繁殖功能并形成精子的方法

摘要

The invention relates to a process for increasing the sexual activity of birds and useful domestic mammals and for preparing spermatozoa suitable to their propagation. The process of the invention comprises treating sexually mature male birds or useful domestic mammals at least twice and at most four times with 0.1 to 5 mu g/kg of body weight of a compound of the general formula (I), Glp-His-Trp-Ser-Tyr-X1-Leu-Arg-Pro-X4 (I) wherein X1 stands for a glycyl group, a natural or synthetic aminoacid or aminoacid derivative of D configuration, an -Asp-Q group of L configuration, wherein Q is attached to the alpha -carbonyl moiety of the aspartyl group and represents a C1-5 alkylamide, an arylamide, a C1-4 alkoxy or a benzyloxy group; and X4 stands for a glycylamide or a C1-4 alkylamide group, while keeping a pause of at least 30 hours and at most 72 hours between the consecutive treatments. The process of the invention can mainly be used in such large-scale breedings, where artificial insemination is employed but it can be used also for any domestic bird or cought wild-fowl and ornamental bird as well as useful domestic mammal under the conditions of the natural reproduction or artificial insemination.
机译:本发明涉及一种提高鸟类和有用的家养哺乳动物的性活动并制备适合其繁殖的精子的方法。本发明的方法包括用0.1至5μg/ kg体重的通式(I)化合物Glp-His-Trp处理性成熟的雄禽或有用的家养哺乳动物至少两次且至多四次。 -Ser-Tyr-X1-Leu-Arg-Pro-X4(I),其中X1代表缩水甘油基,D构型的天然或合成氨基酸或氨基酸衍生物,L构型的-Asp-Q基团,其中Q为连接至天冬氨酰基的α-羰基部分并代表C 1-5烷基酰胺,芳酰胺,C 1-4烷氧基或苄氧基; X 4代表甘氨酰胺基或C 1-4烷基酰胺基团,同时在连续治疗之间保持至少30小时和至多72小时的停顿。本发明的方法可主要用于采用人工授精的大规模育种中,但也可用于任何家禽或人工饲养的野禽和观赏鸟以及在这种条件下有用的家养哺乳动物。自然繁殖或人工授精。

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