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tumor antigen, method for the production thereof and the use of the antigen for diagnosis of human tumours
tumor antigen, method for the production thereof and the use of the antigen for diagnosis of human tumours
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机译:肿瘤抗原,其生产方法以及该抗原在诊断人类肿瘤中的用途
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摘要
Disclosed are monoclonal antibodies which react with human tumor cells, particularly metastatic human tumor cells, but not with normal human tissues tested. The monoclonal antibodies are prepared against a 580 kilodalton glycoprotein antigen, designated gp580, which is isolated from either rat or human tumor cells. Methods for isolating the glycoprotein antigen are disclosed as well. Moveover, techniques are disclosed for utilizing these antibodies both in the detection and in the prevention of human tumor lesions.
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