human antibody or binding fragment thereof, antigen, polynucleotide, vector, host cell, method for preparing an antibody or immunoglobulin binding fragment or chain (s) thereof, antibody, immunoglobulin chain or binding fragment thereof , composition, uses of the antibody or binding fragment, an antigen, a polynucleotide, a vector, or a cell, and a tumor antigen binding molecule, method for molecular cloning of an antibody, and kit for the diagnosis of a tumor

摘要

human antibody or binding fragment thereof, antigen, polynucleotide, vector, host cell, method for preparing an antibody or immunoglobulin binding fragment or chain (s) thereof, antibody, immunoglobulin chain or binding fragment thereof , composition, uses of the antibody or binding fragment, an antigen, a polynucleotide, a vector, or a cell, and a tumor antigen binding molecule, methods for treating or preventing the progression of a tumor in a individual; to improve symptoms associated with a tumor; to diagnose or examine an individual for the presence of a tumor, or to determine the individual's risk of developing a tumor, to diagnose and / or treat a tumor-related disorder, and to molecularly clone an antibody; Diagnosis of a tumor New human tumor-specific antibodies are provided, as well as fragments, derivatives and variants that recognize the ny-es0-1 antigen associated with the tumor. furthermore, pharmaceutical compositions containing such antibodies and mimics thereof in the treatment of tumors are described.