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varicella zoster virus (vzv), method for manufacture thereof, and vaccine containing the vzv
varicella zoster virus (vzv), method for manufacture thereof, and vaccine containing the vzv
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机译:水痘带状疱疹病毒(vzv),其制造方法以及含有vzv的疫苗
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摘要
A vaccine strain of varicella-zoster virus (VZV), tested in clinical trials, is capable of preventing chickenpox in children. This virus has been modified by the introduction into its genome of heterologous DNA which encodes an immunogenic polypeptide of another human pathogen. This heterologous polypeptide is expressed in cells infected by the recombinant virus. Such recombinant VZV is useful as a vaccine for chickenpox as well as for heterologous pathogens.
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