PROCESS FOR THE PREPARATION OF 1-3,4-DIMETOXIPHENETYL-AMINO- 3-(M-TOLYOXI)-2-PROPANOL (BEVANTOLOL)

摘要

There is disclosed a process for preparing a compound of the following general formula CHEM wherein Z is a lower (C1-4) alkoxy, chloro, cyano, hydroxyalkyl, aryl, m-lower (C1-4) alkyl, or o-vinylic; which process comprises (1) reacting a compound of the following general formula CHEM with beta-(3, 4-dimethoxyphenyl) ethylamine having the formula CHEM at a temperature of 20 C or less than 20 C m