procedure for continuous cultivation of bacillus stearothermophilus whereby bacterial cells with high content acetatkinas erhalles

摘要

A process is described for cultivating thermophilic bacteria of the genus Bacillus having the ability to produce acetate kinase, wherein said cultivation is carried out continuously at a dilution rate (D) in the range from about 0.9 mu max to 1.0 mu max, wherein D is the dilution rate (1/hr), and mu max is the maximum specific growth rate (1/hr), to thereby produce bacterial cells having a high content of acetate kinase.