device for restoring the content of air in the cylinders to lung to regulate the water pressure with the use of pumps with intermittent operation

• 1. 利用空气顶托密封运行时又不外泄泵内液体分子且包括深潜泵在内的泵结构及水陆使用方法 [P] . 中国专利： CN113309709A . 2021-08-27
• 2. 利用空气顶托密封运行时又不外泄泵内液体分子且包括深潜泵在内的泵结构及水陆使用方法 [P] . 中国专利： CN113279972A . 2021-08-20
• 3. device for restoring the content of air in the cylinders to lung to regulate the water pressure with the use of pumps with intermittent operation [P] . IT1192509B . 1988-04-20

  机译： 使用间歇运行的泵将气瓶中的空气含量恢复到肺部以调节水压的装置

• 4. device for restoring the content of air in the cylinders to lung to regulate the water pressure with the use of pumps with intermittent operation [P] . IT8209512D0 . 1982-09-15

  机译： 使用间歇运行的泵将气瓶中的空气含量恢复到肺部以调节水压的装置

• 5. Device for restoring the air content in hydraulic storage containers for regulating the delivery of water held under pressure by means of intermittently driven pumps [P] . 德国专利： DE3223865A1 . 1983-02-17

  机译： 用于恢复液压存储容器中空气含量的装置，以通过间歇驱动泵调节在压力下保持的水的输送

• 1. Effect of the adaptive intermittent ventilation before radical operation for lung cancer under one-lung ventilation on the non-ventilated lung tissue injury and apoptosis molecule protein expression [J] . Xue-Mei Yang 海南医科大学学报（英文版） . 2017,第018期
• 2. Effect of the adaptive intermittent ventilation before radical operation for lung cancer under one-lung ventilation on the non-ventilated lung tissue injury and apoptosis molecule protein expression [J] . Xue-Mei Yang 海南医科大学学报(英文版) . 2017,第018期
• 3. Exciting Forces for a Wave Energy Device Consisting of a Pair of Coaxial Cylinders in Water of Finite Depth [J] . Mohammad Hassan, Swaroop Nandan Bora 船舶与海洋工程学报（英文版） . 2013,第003期
• 4. Feasibility Analysis of Back-Pressure Steam Feeding Water Pump for Direct Air-Cooled Unit [J] . Zhao Xiaodong, Wang Meng, Du Xiaoze, 电气（英文版） . 2013,第001期
• 5. Heat transfer analysis of groundwater flow for ground heat exchangers in the multi-borehole field of ground source heat pump under the intermittent operation [C] . Cancan Zhang, Yuejin Yu International Conference on Manufacturing Engineering and Process . 2014
• 6. Validation of the airflow perturbation device and the pressure flow characteristics of excised sheep lungs. [D] . Sahota, Manjit Singh. 1998
• 7. Low suction on digital drainage devices promptly improves post-operative air leaks following lung resection operations: a retrospective study [O] . Suguru Mitsui, Shunsuke Tauchi, Takahiro Uchida, 2021
• 8. METHOD AND DEVICE FOR RESTORING THE PLUNGER PAIR OF A HIGH-PRESSURE FUEL PUMP [O] . 2020

• 1. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 2. 长管拖车气瓶外测法水压试验装置校验问题探讨 [C] . Geng Hui-po ,耿会坡 ,Fan Yun-lu . 2018特种设备安全与节能学术会议 . 2018
• 3. 基于气液增压的气瓶水压试验装置控制系统设计 [A] . 张殿鑫 . 2017