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A method for preparing a composition based parmaceutica a corticosteroid.

机译:一种制备基于组合物的parmaceutica和皮质类固醇的方法。

摘要

Preparation method of Base compositions for topical Application of Corticosteroids.Includes mixing intimately at a temperature between 0jc and 60jc, 0.01 to 10% of a corticosteroid, 0 - 80% of a Solvent, such as water, ethanol or 2-propanol, 10 - 99.9% of a vehicle penetration Enhancer consisting of a desordenador diol and a compound of the cell envelope.And optional Additives known compositions of this kind; adjust the mixture so that the weight ratio of diol to desordenador Compound is 1: 1 to 500: 1; and making the mixture free of straight chain saturated fatty alcohols and acids c16-20 mono - or di unsaturated carboxylic CAD Ena linear C4 - 20.These compositions have applications for the Topical Treatment of inflammatory States.
机译:用于局部应用皮质类固醇的基础组合物的制备方法,包括在0jc至60jc之间的温度下紧密混合,将0.01-10%的皮质类固醇,0-80%的溶剂(如水,乙醇或2-丙醇),10- 99.9%的车辆渗透促进剂,由去酚醛二醇和细胞被膜化合物组成。调节混合物,使二醇与去杂多酚化合物的重量比为1:1至500:1;使该混合物不含直链饱和脂肪醇和酸c16-20单或二不饱和羧酸CAD Ena线性C4-20。这些组合物可用于炎症状态的局部治疗。

著录项

  • 公开/公告号ES8608876A1

    专利类型

  • 公开/公告日1986-12-16

    原文格式PDF

  • 申请/专利权人 THE PROCTER & GAMBLE COMPANY;

    申请/专利号ES19840533578

  • 发明设计人

    申请日1984-06-20

  • 分类号A61K31/56;

  • 国家 ES

  • 入库时间 2022-08-22 07:17:15

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