A process for the preparation of Derivatives of secocantina

摘要

Preparation method of Derivatives of secocantina. To obtain compounds of formula (i), wherein R1 is Hydrogen, halogen, alkoxy or alkyl; R2 and R3 is Hydrogen or a joint Link; R4 and R5 is Hydrogen or an oxo Group; R7 R6 is Hydrogen or alkyl; and choose between different radicals.By condensation of the compound of formula (ii) with hydroxylamine, followed by reaction with a primary or secondary Amine. Optionally can transform some radicals and obtained a Salt of pharmacological interest. Application antihipoxica activity and to address the lack of Oxygen to the Brain.