New purified glycoproteins from cow, horse and sheep and use in diagnosing infectious mononucleosis

摘要

Preparations useful in the diagnosis of infectious mononucleosis are disclosed. Cow, horse and sheep erythrocytes are purified and essentially homogeneous glycoproteins are extracted. A less purified form of bovine glycoprotein is also described. The purified glycoproteins are useful as antigens in immunoassays for the presence of the heterophile antibodies of infectious mononucleosis, and in the preparation of reagents for the enumeration of rosetting lymphocytes without having to have available fresh sheep blood.