ANTIMICROBIAL COMPOSITIONS CONTAINING 1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(1-PIPERAZINYL)-3-QUINOLINE CARBOXYLIC ACID OR METAL SALTS THEREOF AND SILVER SULFADIAZINE.

摘要

compositions comprising the carboxylic acid of 1 - ethyl - 6 - fluoro 1,4 dihydro 4 oxo - (1-piperazinyl) - quinoline or its salts, metal salts, such as silver, zinc,cobalt, cerium and silver sulfadiazine, effective in the treatment of burns.of particular interest are compositions containing silver sulfadiazine and silver salt of quinoline carboxylic acid as identified above.the resulting compositions are effective, even if the compound is present in a concentration which would be ineffective if the compound was used separately.the compositions of the present invention can be applied on the surface of a burn victim is concerned directly.in combination with a physiologically acceptable medium, such as a hydrophilic carrier which can be dispersed in the water.