Monoclonal antibodies to Pseudomonas aeruginosa exoenzyme S, their preparation and use

摘要

Monoclonal antibodies to P. aeruginosa exoen­zyme S are prepared from hybrid cell lines. The antibo­dies may be of any isotype and may be of any origin such as murine or human origin. Antibodies that exhibit the ability to neutralize the adverse biological effects of the exoenzyme may be used to treat infections caused by P. aeruginosa.