PROCESS FOR FACILITATING THE FORMATION OF LIPID SPHERULES DISPERSION IN AN AQUEOUS PHASE AND FOR IMPROVING THEIR STABILITY AND THEIR ENCAPSULATION RATE, AND CORRESPONDING DISPERSIONS.

摘要

P THIS PROCESS ALLOWS TO FACILITATE THE FORMATION OF LIPID SPHERULES IN DISPERSION IN AN AQUEOUS MEDIUM D AND TO SIMULTANEOUSLY IMPROVE THE STABILITY AND THE INCAPSULATION RATE OF SUCH LIPID SPHERULES, WHICH ARE CONSISTING OF LIPIDICULAR SHEETS. AN AQUEOUS PHASE E, THE LIPIDS CONSTITUTING THE SHEETS BEING IONIC OR NON-IONIC AMPHIPHILES. FOR THIS PURPOSE, BEFORE THE FORMATION OF THE SAID SPHERULES, CHOLESTEROL SULFATE, FROM 1 TO 50 BY WEIGHT OF THE LIPID PHASE WEIGHT, IS ADDED TO THE LIPIDS INTENDED TO CONSTITUTE THE SPHERULA SHEETS. /P