首页>
外国专利>
Method of inducing local anesthesia using microdroplets of a general anesthetic
Method of inducing local anesthesia using microdroplets of a general anesthetic
展开▼
机译:使用全身麻醉药的微滴诱导局部麻醉的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
Local anesthesia is induced using microdroplets of a general anesthetic in liquid form. As an example, microdroplets of the general anesthetic methoxyfluorane coated by a unimolecular layer of dimysistoyl phosphatidylcholine are prepared by sonication. The microdroplets so prepared remain stable in physiologically-compatible solution, and are suitable for injection, typically intradermally or intraveneously, into a patient for inducing local anesthesia. These methoxyflurane-containing microdroplets have been demonstrated to cause long-term local anesthesia when injected intradermally, giving duration of anesthesia 28 times longer than with other anesthetics, such as lidocaine and 11 times longer than with bupivacaine.
展开▼