Immunotherapeutic polypeptide agents which bind to lymphocyte immunoglobulin FC receptors

摘要

An active site peptide which blocks immune complex binding to Fc receptors, the peptide having an amino acid sequence selected from the group consisting of: ##EQU1## or a subgroup thereof, whereinP PA is Arg, Lys, Orn, Gln, or His;PPB is Ser, Thr, Ala, or Gly;PPC is Thr, Ser, Ala, or Gly;PPD is Thr, Ser, Ala, or Gly;PPE is Lys, Arg, Orn or His; PPF is Thr, Ser, Ala, or Gly;PPG is Ser, Thr, Ala, or Gly;PPH is Gly, Ala, Thr, Ser, Lys, Arg, or OrnPPI is Pro, Val, Leu, Ile, or Ala;PPJ is Arg, Lys, Orn, or His;PPK is Ala, Thr, Ser, or Gly; PPL is Ala, Thr, Ser, or Gly;PPM is Pro, Val, Leu, Ile, or Ala;PPN is Glu, or Asp;PPO is Val, Leu, Ile, or Ala;PPP is Tyr, or Phe.P Pand pharmaceutically acceptable salts thereof.