首页> 外国专利> N-substituted-2- 2- 2-(4-phenylpiperazine-1-yl)ethoxy!phenyl!- thiazolidine-3-carboxamides useful as cardiotonic agent

N-substituted-2- 2- 2-(4-phenylpiperazine-1-yl)ethoxy!phenyl!- thiazolidine-3-carboxamides useful as cardiotonic agent

机译:N-取代的-2--2-(4-(4-苯基哌嗪-1-基)乙氧基!苯基!-噻唑烷-3-羧酰胺可用作强心药

摘要

A novel thiazolidine derivative of the formula: ##STR1## wherein R.sup. 1 is a substituted or unsubstituted phenyl group, Q is a single bond, a lower alkylene group or a lower alkenylene group, R.sup.2 and R.sup.3 are the same or different and each is hydrogen atom, a lower alkyl group, a cycloalkyl group, a lower alkanoyl group, a lower alkoxycarbonyl group, a lower alkylsulfonyl group, a benzoyl group, a phenyl group or a di(lower alkyl)phosphoryl group, Alk is a lower alkylene group, and Y and Z are the same or different and each is oxygen atom or sulfur atom, or a pharmaceutically acceptable salt thereof, which is useful as a cardiotonic agent is disclosed together with processes for the preparation of the compound and a pharmaceutical composition containing said compound.
机译:新型的噻唑烷衍生物,其分子式为: 1是取代或未取代的苯基,Q是单键,低级亚烷基或低级亚烯基,R 2和R 3相同或不同,并且各自为氢原子,低级烷基基,环烷基,低级烷酰基,低级烷氧羰基,低级烷基磺酰基,苯甲酰基,苯基或二(低级烷基)磷酰基,Alk为低级亚烷基,且Y和Z为公开了用作强心药的相同或不同的且各自为氧原子或硫原子或其药学上可接受的盐,以及该化合物的制备方法和包含所述化合物的药物组合物。

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