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CHALCONE DERIVATIVE AND ANTIULCER AGENT CONTAINING SAID CHALCONE DERIVATIVE AS ACTIVE INGREDIENT
CHALCONE DERIVATIVE AND ANTIULCER AGENT CONTAINING SAID CHALCONE DERIVATIVE AS ACTIVE INGREDIENT
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机译:包含所述查尔酮衍生物作为活性成分的查尔酮衍生物和抗氧化剂剂
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NEW MATERIAL:A compound expressed by formula I (X and Y are H or together form a direct bond; R1 is H or carboxymethoxy; R2 is H, isoprenyl, isopentyl or propyl,; R3 is OH or methoxy; R4 and R5 are H or R3; R6 is R3 or carboxymethoxy; R7 is H or methoxy, provided that at least one of R3-R6 is methoxy when R2 is H; R1 is carboxymethoxy, etc., when R2 is isoprenyl). EXAMPLE:1-(2,4,6-Trihydroxy-3-isopentylphenyl)-3-(4-hydroxy-3-methoxyp henyl-1- propanone. USE:An antiulcer agent capable of withstanding continuous use for a long period with hardly any side effects. PREPARATION:A compound expressed by formula II obtained from acetophenone, etc. is condensed with a compound expressed by formula III in an organic solvent using a base to afford the aimed compound expressed by formula I.
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