首页> 外国专利> nitrogen, maettede, dinuclear cyclopentaringholdige diphosphonsyrer and pharmaceutical association including these

nitrogen, maettede, dinuclear cyclopentaringholdige diphosphonsyrer and pharmaceutical association including these

机译:氮,双酯,双核环戊二烯二膦和包括这些的药物协会

摘要

The present invention relates to novel compounds having nitrogen-containing, saturated bicyclic cylopentane-fused rings which are geminally disubstituted with phosphonate groups. Most preferred compounds of the present invention have the general structure: CHEM The present invention further relates to pharmaceutical compositions containing these novel compounds. Finally, this invention relates to methods for treating or preventing diseases characterized by abnormal calcium and phosphate metabolism by utilizing a compound or pharmaceutical composition of the present invention.
机译:本发明涉及具有含氮的饱和双环环戊烷稠合环的新型化合物,其被膦酸酯基团双取代。本发明最优选的化合物具有一般结构:本发明进一步涉及含有这些新化合物的药物组合物。最后,本发明涉及通过利用本发明的化合物或药物组合物治疗或预防以钙和磷酸盐代谢异常为特征的疾病的方法。

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