NEW PROCESS FOR PREPARING 1,6-DIBROMO-DIDEOXY-D-MANNITOL AND 1,6-DIBROMO-DIDEOXY-DULCITOL

摘要

1,6-diibromo-di:desoxy -D-mannitol or 1,6-di:bromo-di:dezoxy -dulcitol is prepd. from D-mannitol or from Dulcitol. - These cpds. are subjected to the action of aq. Hydrogen-bromide in an enclosed space under 4-8 bar constant pressure ast 50-90 deg. C for 5-20 hours. The molar ratio of water to hydrogen bromate is kept constant below 2.5 by continuous addition of hydrogen-bromide from an external source. - The raw product is recrystallized without drying, from a water miscible solvent.