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MODIFIED VARICELLA-ZOSTER VIRUS,ITS PRODUCTION AND VACCINE CONTAINING IT
MODIFIED VARICELLA-ZOSTER VIRUS,ITS PRODUCTION AND VACCINE CONTAINING IT
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机译:改良的水痘-带状疱疹病毒,其生产和疫苗接种
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摘要
A vaccine strain of varicella-zoster virus (VZV), tested in clinical trials, is capable of preventing chickenpox in children. This virus has been modified by the introduction into its genome of heterologous DNA which encodes an immunogenic polypeptide of another human pathogen. This heterologous polypeptide is expressed in cells infected by the recombinant virus. Such recombinant VZV is useful as a vaccine for chickenpox as well as for heterologous pathogens.
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