13 - ACYLOXY - 5 - KETOMILBEMYCIN DERIVATIVES AND PREPARATION OF 13 - HYDROXY - 5 - KETOMILBEMYCIN DERIVATIVES

摘要

13-Hydroxy-5-ketomilbemycin derivatives are prepared by oxidizing a 5-ketomilbemycin with selenium dioxide in the presence of a lower aliphatic carboxylic acic. A range of new 13-acyloxy-5-ketomilbemycins and a method or preparing them are also disclosed.