PROCESS FOR PREPARING 13-HYDROXY-5-KETOMILBEMYCIN DERIVATIVES AND 5-KETOMILBEMYCIN DERIVATIVES UTILIZABLE THEREIN

摘要

13-Hydroxy-5-ketomilbemycin derivatives are prepared by oxidizing a 5-ketomilbemycin with selenium dioxide in the presence of a lower aliphatic carboxylic acic. A range of new 13-acyloxy-5-ketomilbemycins and a method or preparing them are also disclosed.