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COMPOUNDS OBTAINED FROM THE ASSOCIATIVE SYNTHESIS OF SULFUR-CONTAINING OR SULFUR-FREE AMINO ACIDS WITH PREGNANE DERIVATIVES

机译:含硫或无硫氨基酸与戊烷衍生物的缔合所获得的化合物

摘要

Compounds obtained from the associative synthesis of sulfur-containig or sulfur-free amino-acids with derivatives of Δ-4 pregnene 3,20-dione or with derivatives of Δ-1,4 pregnadiene 3,20-dione having the general formulae (I), (II), and (III), having glucocorticoide and anti-inflammatory properties have been prepared and tested. The pharmaceutical compositions, the medicaments containing them as well as their applications are claimed, particularly in the cutaneous and ophthalmic fields.
机译:含硫或无硫氨基酸与Δ-4孕烯3,20-二酮的衍生物或Δ-1,4孕二烯3,20-二酮的衍生物的缔合合成的具有通式(I)的化合物),(II)和(III)具有糖皮质激素和抗炎特性已被制备和测试。要求保护药物组合物,包含它们的药物及其应用,特别是在皮肤和眼科领域。

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