FUSED-SILICA MICROBORE PACKED CHROMATOGRAPHY COLUMN WITH CHEMICALLY MODIFIED COLUMN WALL

摘要

A packed, microbore fused-silica column (10) for use in liquid chromatography, wherein the column wall has been chemically modified, is shown. The chemical modification of the column wall is used to modify and improve the performance of the column (10). In one embodiment a stationary phase (20), different than the stationary phase bonded to the packing material (25), is bonded to the column wall. For reasons that are not yet understood column performance may be greatly enhanced.