Process and apparatus for measuring the parameters characterizing the microbiological interactions between phages and bacteria

摘要

A process and an apparatus are described for determining the quantities characterizing tne phage development cycle starting at the interaction between virulent phages and host-bacteria within the duration of approx. one single burst. These parameters enable determination of expectable phage-yield, duration and standard deviation of phage development, multiplicity of infection. which are determined by the apparatus from signals in correlation with the number of bacteria (e.g. optical scattering). By collecting a proper programme the apparatus is well suitable for the quantitative determination of the biological response (parameter-change) occuring at the change in the environment resp. state of the phages behaving as unliving obiects, the bacteria and complexes and as a result of their interaction.