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(substituted-phenyl)-5-oxo-2-pyrrolidinepropanoic acids, a process for producing the compounds and pharmaceutical compositions comprising the compounds

机译:(取代的苯基)-5-氧代-2-吡咯烷丙酸,制备所述化合物的方法和包含所述化合物的药物组合物

摘要

Compounds of formula I or II …CHEM… wherein R is a hydrogen, a pharmaceutically acceptable metal or amine cation, an alkyl radical of from one to six carbon atoms, a phenyl radical, or a phenylmethyl radical; and wherein X and Y are independently a hydrogen, an alkyl radical of from one to six carbon atoms, an alkoxy radical of from one to six carbon atoms, a chlorine or a trifluoromethyl radical. A process for preparing the compounds and pharmaceutical compositions comprising the compounds are also disclosed, The compounds are useful in the treatment of senility and for reversing amnesia.
机译:式I或II的化合物...其中R是氢,药学上可接受的金属或胺阳离子,具有1-6个碳原子的烷基,苯基或苯基甲基;其中X和Y独立地是氢,1-6个碳原子的烷基,1-6个碳原子的烷氧基,氯或三氟甲基。还公开了制备所述化合物的方法和包含所述化合物的药物组合物。所述化合物可用于治疗衰老和逆转健忘症。

著录项

  • 公开/公告号EP0164853B1

    专利类型

  • 公开/公告日1988-07-06

    原文格式PDF

  • 申请/专利权人 WARNER-LAMBERT COMPANY;

    申请/专利号EP19850302949

  • 发明设计人 BUTLER DONALD E.;THOMAS ANTHONY J.;

    申请日1985-04-26

  • 分类号C07D207/267;A61K31/40;

  • 国家 EP

  • 入库时间 2022-08-22 06:55:50

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