Chromoglycic acid derivatives represented by following general formula (I): wherein R1 represents H or an α-, β- or η-amino acid residue (ester bonding) optionally substitued by a lower alkyl group at its amino group, and R?2 and R3¿ each represents a lower alkyloxy-substituted or unsubstituted lower alkyl group, a 1-alkanoyloxyalkyl group, a 1-alkoxycarbonyloxyalkyl group, a phthalidyl group or a 5-methyl-1,3-dioxol-2-on-4-ylmethyl group, provided that, when R1 represents H, R?2 and R3¿ represent groups other than a lower alkyl group and a 1-alkanoyloxyalkyl group or nontoxic salts thereof, a process for their preparation, and a medicinal composition containing the same. The compounds have an anti-allergic effect, and can be easily absorbed in blood by oral administration, thus being useful as an anti-allergic agent for oral administration.
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机译：由以下通式（I）表示的色甘氨酸衍生物：其中R1代表H或任选地在其氨基处被低级烷基取代的α-，β-或η-氨基酸残基（酯键）。 R 3分别表示低级烷氧基取代或未取代的低级烷基，1-烷酰氧基氧基烷基，1-烷氧基羰氧基氧基烷基，邻苯二甲酰基或5-甲基-1,3-二氧杂-2--2--4-基甲基前提条件是，当R 1代表H时，R 2和R 3代表除低级烷基和1-链烷酰氧基烷基以外的基团或其无毒盐，其制备方法和含有它们的药物组合物。该化合物具有抗过敏作用，并且可以通过口服容易地吸收到血液中，因此可用作用于口服的抗过敏剂。
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