Process for the preparation of adenosine3 ′, 5 ′ - monophosphate n6 - substituted cyclic or of the corresponding salts

摘要

Process for the preparation of adenosine 3, 5 - monophosphate n - substituted cyclic or of a corresponding salt, the to prepare these compounds represented by the general formula: & br / (see appended drawing in bopi) & br / in which r is a straight or branched alkyl radical with 1 has 13atomes of carbon or an aromatic radical and b denotes an ion, 1996, or an alkali metal ion is react an adenosine 3, 5 - monophosphate cyclic, or a salt of the general formula: & br / (see appended drawing in bopi) & br / or a represents an ion, 1996, an alkali metal ion, an ammonium ion organic or an ammonium ion with an aldehyde of general formula: rcho (iii) or r is as defined above - above has a ph of 7,0 or less between - 10 and 120c with a molar ratio of (ii) to (iii) e 11 - 40 and is reduced, the composed obtained with a metal hydride or of the nascent, 1996.