首页> 外国专利> Method of analysis of the peptide sequences immunogenic containing an feature of a protein foreign to the body of a host organism, in view of the production of vaccines

Method of analysis of the peptide sequences immunogenic containing an feature of a protein foreign to the body of a host organism, in view of the production of vaccines

机译:考虑到疫苗的生产,分析具有免疫原性的肽序列的方法,所述肽具有宿主生物体机体外源性蛋白质的特征

摘要

Method for analyzing peptide sequences carrying an epitope characteristic of an antigenic protein to the organism of a host. Said method comprises the detection of those tetrapeptidic sequences contained in the antigenic protein which have no counterpart in a data bank gathering information relative to the amino acid sequences of the proteins of the ''somatic self'' of the host. The synthesis of the peptidic sequences is carried out and their capacity to induce in vivo antibodies active against all of the protein is tested.
机译:分析携带对宿主生物体具有抗原蛋白特征性表位的肽序列的方法。所述方法包括检测抗原蛋白中包含的那些四肽序列,这些四肽序列在数据库中没有对应物,从而收集与宿主“体细胞自身”的蛋白的氨基酸序列有关的信息。进行肽序列的合成,并测试其诱导对所有蛋白质具有活性的体内抗体的能力。

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