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Synthetic resin matrix drug storage and topical drug delivery dressing for veterinary usage

机译:兽用合成树脂基质药物存储和局部药物输送敷料

摘要

A synthetic resin matrix dressing is disclosed consisting essentially of a polymer, such as poly(2-hydroxyethylmethacrylate), referred to as PHEMA, an organic solvent, such as polyethylene glycol (PEG), and a hydrogen bonding plasticizer, such as dimethylsulfoxide (DMSO). The plasticizer regulates the set-up time of the synthetic resin so that the more plasticizer present, the shorter the set-up time. The dressing may be applied to the treatment site in veterninary use in the form of a paste for the in-situ curing or setting thereof, or the dressing may be preformed and then applied to the treatment site. A variety of drug agents may be incorporated in the synthetic resin matrix so as to result in the time released administration of the drug agent to the area of the skin covered by the dressing. A method of treatment using this dressing is also disclosed.
机译:公开了一种合成树脂基质敷料,其主要由聚合物(例如称为PHEMA的聚(2-甲基丙烯酸羟乙酯),有机溶剂(例如聚乙二醇(PEG))和氢键增塑剂(例如二甲基亚砜)(DMSO)组成)。增塑剂调节合成树脂的凝结时间,使得存在的增塑剂越多,凝结时间越短。敷料可以以糊剂的形式用于兽医用途中的治疗部位以用于原位固化或固化,或者可以预先形成敷料然后施加到治疗部位。可以将多种药物试剂掺入合成树脂基质中,以导致将药物试剂释放至敷料覆盖的皮肤区域的时间释放。还公开了一种使用该敷料的治疗方法。

著录项

  • 公开/公告号US4725271A

    专利类型

  • 公开/公告日1988-02-16

    原文格式PDF

  • 申请/专利权人 ENQUAY PHARMACEUTICAL ASSOCIATES;

    申请/专利号US19850802421

  • 发明设计人 BERNARD KOROL;

    申请日1985-11-27

  • 分类号C08K5/41;C08K5/34;C08K5/15;C08K5/10;

  • 国家 US

  • 入库时间 2022-08-22 06:49:28

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