NOVEL DRIMANE-TYPE SESQUITERPENE CARBOXYLIC ACID DERIVATIVE

摘要

NEW MATERIAL:The drimane-type sesquiterpene carboxylic acid derivative of formula (R1 is H, OH or lower alkanoyloxy; R2 is H or lower alkyl; R3 is H or lower alkyl; R4 is =CH2 or O; R1 and R2 may together form a single bond) and its salt. USE:A medicine effective in removing active oxygen seed and preventing or suppressing the formation of lipid peroxide in the body. For example, an antiulcer agent for peptic ulcer, remedy for the disorder of various tissue cells of liver, kidney, pancreas, etc., remedy for autoimmune diseases, remedy for cardiac ischemic diseases, preventive for cancer, anti-inflammatory agent and preventive for aging. PREPARATION:The compound of formula can be extracted and separated from Cryptoporus volvatus which is a fungus of family Polyporaceae.