PTELISINE DERIVATIVE AND PREPARATION HAVING ANTIARRHYTHMIC ACTION AND DIUTERIC ACTION CONTAINING THE SAME

摘要

A pharmaceutically efficacious pteridine compound of formula: IMAGE I wherein R1 is hydrogen, halogen, trifluoromethyl, nitro, a -(A)n-OR3 group, wherein R3 is hydrogen or a C1-6 alkyl group, a -(A)n-NR4R5 group, wherein R4 and R5 independently of each other are hydrogen or a C1-6 alkyl group or R4 and R5 together with the nitrogen atom form a 5- or 6-membered ring that is substituted with a C1-4 alkyl group and wherein A is a linking group having 1 to 6 linking carbon atoms, one of which can be replaced by oxygen and wherein n is zero or one, and wherein R2 is hydrogen or, independently of R1, has the same meaning as R1, with the proviso that R1 and R2 are not simultaneously hydrogen, and the physiologically acceptable acid addition salts thereof.